Nanotechnology
Andrij Holian, Ph.D. (Nanotechnology, Lung Fibrosis, Particles, Methamphetamine, Epigenetics and Diet)
- Characterize mechanisms of particle and nanoparticle uptake by macrophages and the potential role of scavenger receptors in regulating lung inflammation
- Defining the mechanisms of particle-induced lysosomal disruption leading to NLRP3 inflammasome activation and characteristics of nanoparticles leading to lung pathology
- Characterize the role of the innate immune response by macrophages contributing to acute and chronic inflammation