Information on Tiered Rates
*Industrial/commercial users should enquire for a quote specific to your project.*
Tier | Who is included in this tier | Cost calculation |
---|---|---|
Tier 1 users | 猎奇重口, UM western, UM Helena, and 猎奇重口 Tech | Base rate |
Tier 2 users | Other MUS academic, MT governmental agencies, Tribal Colleges, and all non-profits | Base rate + 25% |
Tier 3 users | Non-MUS academic, federal organizations | Base rate + IDC rate ( currently 47%) |
*Fee Structure Valid thru June 30, 2025 (fee structure will be updated annually, please anticipate a 5% increase for future dates)
Instrument Use
Instrument | Tier 1 Rate | Tier 2 Rate |
Tier 3 Rate |
---|---|---|---|
AKTA FPLC Staff run: Self run: |
$150 $110 |
$187.50 $137.50 |
$220.50 $161.70 |
Tycho (NanoTemper Thermofluorescence) Staff run: Self run: |
$10 $1 |
$12.50 $1.25 |
$14.70 $1.47 |
HPLC_MALS per run charge only + staff time Staff run only: |
$150 |
$187.50 |
$220.50 |
ITC Staff run: Self run: |
$50 $30 |
$62.50 $37.50 |
$73.50 $44.10 |
Biacore X100 per day (no analysis) Staff run only: |
$480 |
$600 |
$705.60 |
Biacore X100 per day (user supplies matrix chip) Staff run only: |
$180 |
$225 |
$264.60 |
Scorpion (user provides reagents) Staff run: Self run: |
$60 $40 |
$75 $50 |
$88.20 $58.80 |
NT8 Formulatrix Robot Setup (96 well crystal screen) Staff run: Self run: |
$100 $90 |
$125 $112.50 |
$147 $132.30 |
24 well crystallization plate Staff run: Self run: |
$70 $25 |
$87.50 $31.25 |
$102.90 $36.75 |
Sonicator* Staff run: Self run: |
$30 $10 |
$37.50 $12.50 |
$44.10 $14.70 |
Avestin* Staff run: Self run: |
$110 $70 |
$137.50 $87.50 |
$161.70 $102.90 |
Sorvall medium Speed* Staff run: Self run: |
$70 $50 |
$87.50 $62.50 |
$102.90 $73.50 |
Beckman Ultra* Staff run: Self run: |
$70 $50 |
$87.50 $62.50 |
$102.90 $73.50 |
Shaker* Staff run: Self run: |
$50 $10 |
$62.50 $12.50 |
$73.50 $14.70 |
SDS PAGE (1 gel, Coomassie stain, digital scan)* Staff run: Self run: |
$60 $20 |
$75 $25 |
$88.20 $29.40 |
Western (user-supplied or in-stock Ab)* Staff run: Self run: |
$80 $40 |
$100 $50 |
$117.60 $58.80 |
Consumable Unit Cost | At cost |
*staff rates for these items may be charged as additional costs for protein expression and purification projects
X-RAY CRYSTALLOGRAPHY
Instrument | Tier 1 Rate | Tier 2 Rate | Tier 3 Rate |
---|---|---|---|
In-House micro-max 007 setup Staff run: Self run: |
$30 $30 |
$37.50 $37.50 |
$44.10 $44.10 |
In-House micro-max 007 beamtime (per hour) Staff run: Self run: |
$70 $40 |
$87.50 $50 |
$102.90 $58.80 |
Synchrotron data collection at Synchrotron (per sample) Staff run: Self run: |
$20 $10 |
$25 $12.50 |
$29.40 $14.70 |
SAXS data collection at Synchrotron (per sample) Staff run: Self run: |
$15 $15 |
$18.75 $18.75 |
$22.05 $22.05 |
Staff Services
Services | Tier 1 Rate | Tier 2 Rate | Tier 3 Rate |
---|---|---|---|
Staff services: Data analysis, structure determination, training, consultation (per hour) |
$47 |
$58.75 |
$69.09 |
*Statement of Work required for Structure determination projects. No charge for consultation on project development
PROTEIN EXPRESSION AND PURIFICATION PRICE GUIDELINES *STATEMENT OF WORK REQUIRED*
from E. Coli strains
Services | Tier 1 Rate | Tier 2 Rate | Tier 3 Rate |
---|---|---|---|
Protein Expression 2L LB, SDS-PAGE, and Western Confirmation Frozen Liq N2 | $490 | $612.50 | $720.30 |
Protein Expression 6L LB, SDS-PAGE, and Western Confirmation Frozen Liq N2 | $650 | $812.50 | $955.50 |
Protein Expression 5L bioreactor LB, SDS-PAGE, and Western Confirmation Frozen Liq N2 | $620 | $775 | $911.40 |
Protein purification 2L, 1 step purification | $720 | $900 | $1,058.40 |
Protein purification 6L, 1 step purification | $1,210 | $1,512.50 | $1,778.70 |
Additional purification step, SDS-PAGE | $200 | $250 | $294 |
from Insect Cells
Services | Tier 1 Rate | Tier 2 Rate | Tier 3 Rate |
---|---|---|---|
Insect Cell, Cellfectin Transfection 6 well plates, to 50 mL P1, SDS-PAGE, Western | $430 | $537.50 | $632.10 |
Insect Cell, virus P2-P3 250 mL, SDS-PAGE, Western | $410 | $512.50 | $602.70 |
Insect Cell Virus 1L Infection, Express 5, freeze in -80C | $400 | $500 | $588 |
Insect Cell Protein 1L prep (one step purification) | $720 | $900 | $1,058 |
from HEK293 cells
Services | Tier 1 Rate | Tier 2 Rate | Tier 3 Rate |
---|---|---|---|
HEK Cell 30 mL test Expression, western to confirm expression | $690 | $862.50 | $1,014.30 |
HEK Cell 200 mL Expression (secreted) | $710 | $887.50 | $1,043.70 |
HEK Cell 200 mL Purification (secreted), 2 step purification | $690 | $862.50 | $1,014.30 |
* Estimated Service fees based on assumption that expression protocols have been established and are known to generate soluble, homogeneous and active products. The costs involved in producing an expression plasmid are not included. An expression test using one or more constructs is recommended if expression conditions have not been determined. Expression and purification of membrane proteins require modified procedures and incur additional costs. Consult with ISBC manager to develop a Statement of Work that includes appropriate milestones and costs.